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Constitutive β(2)-adrenergic signalling enhances sarcoplasmic reticulum Ca(2+) cycling to augment contraction in mouse heart

1. Transgenic overexpression of the β(2)-adrenergic receptor (β(2)AR) in mouse heart augments baseline cardiac function in a ligand-independent manner, due to the presence of spontaneously active β(2)AR (β(2)AR*). This study aims to elucidate the mechanism of β(2)AR*-mediated modulation of cardiac e...

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Detalhes bibliográficos
Main Authors: Zhou, Ying-Ying, Song, Long-Sheng, Lakatta, Edward G, Xiao, Rui-Ping, Cheng, Heping
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269668/
https://ncbi.nlm.nih.gov/pubmed/10581307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00351.x
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