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Human GHRH reduces voltage-gated K(+) currents via a non-cAMP-dependent but PKC-mediated pathway in human GH adenoma cells

1. Whole-cell voltage-gated K(+) currents and the K(+) current response to growth hormone-releasing hormone (GHRH) were characterised in primary cultures of human acromegalic somatotropes. 2. Both delayed rectifier (I(K)) and transient (I(A)) K(+) currents were recorded from human somatotropes held...

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Detalhes bibliográficos
Main Authors: Xu, Ruwei, Roh, Sang-Gun, Loneragan, Kylie, Pullar, Michael, Chen, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269620/
https://ncbi.nlm.nih.gov/pubmed/10545137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00697.x
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