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Muscarinic receptor modulation of GABA-mediated giant depolarizing potentials in the neonatal rat hippocampus

1. The whole-cell patch clamp technique was used to study the role of muscarinic receptors in regulating the frequency of giant depolarizing potentials (GDPs) in CA3 hippocampal neurones in slices from postnatal (P) P1-P8 rats. 2. Atropine (1 μM) reduced the frequency of GDPs by 64·2 ± 2·9%. The ace...

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Bibliografiske detaljer
Main Authors: Avignone, Elena, Cherubini, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269400/
https://ncbi.nlm.nih.gov/pubmed/10373692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.0097r.x
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