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Muscarinic receptor modulation of GABA-mediated giant depolarizing potentials in the neonatal rat hippocampus

1. The whole-cell patch clamp technique was used to study the role of muscarinic receptors in regulating the frequency of giant depolarizing potentials (GDPs) in CA3 hippocampal neurones in slices from postnatal (P) P1-P8 rats. 2. Atropine (1 μM) reduced the frequency of GDPs by 64·2 ± 2·9%. The ace...

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Detalhes bibliográficos
Main Authors: Avignone, Elena, Cherubini, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269400/
https://ncbi.nlm.nih.gov/pubmed/10373692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.0097r.x
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