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Chloride dependence of hyperpolarization-activated chloride channel gates

1. ClC proteins are a class of voltage-dependent Cl(−) channels with several members mutated in human diseases. The prototype ClC-0 Torpedo channel is a dimeric protein; each subunit forms a pore that can gate independently from the other one. A common slower gating mechanism acts on both pores simu...

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Autori principali: Pusch, Michael, Jordt, Sven-Eric, Stein, Valentin, Jentsch, Thomas J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269146/
https://ncbi.nlm.nih.gov/pubmed/10050002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.341ac.x
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