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Molecular dissection of gating in the ClC-2 chloride channel.
The ClC-2 chloride channel is probably involved in the regulation of cell volume and of neuronal excitability. Site-directed mutagenesis was used to understand ClC-2 activation in response to cell swelling, hyperpolarization and acidic extracellular pH. Similar to equivalent mutations in ClC-0, neut...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169762/ https://ncbi.nlm.nih.gov/pubmed/9130703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.7.1582 |
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