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Low-dose expression of a human apolipoprotein E transgene in macrophages restores cholesterol efflux capacity of apolipoprotein E-deficient mouse plasma
Apolipoprotein E- (apoE) deficient (E(−/−)) mice develop severe hyperlipidemia and diffuse atherosclerosis. Low-dose expression of a human apoE3 transgene in macrophages of apoE-deficient mice (E(−/−)hTgE(+/0)), which results in about 5% of wild-type apoE plasma levels, did not correct hyperlipidemi...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The National Academy of Sciences
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22691/ https://ncbi.nlm.nih.gov/pubmed/9636193 |
| タグ: |
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