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Cell Death by SecTRAPs: Thioredoxin Reductase as a Prooxidant Killer of Cells

BACKGROUND: SecTRAPs (selenium compromised thioredoxin reductase-derived apoptotic proteins) can be formed from the selenoprotein thioredoxin reductase (TrxR) by targeting of its selenocysteine (Sec) residue with electrophiles, or by its removal through C-terminal truncation. SecTRAPs are devoid of...

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Bibliografiske detaljer
Main Authors: Anestål, Karin, Prast-Nielsen, Stefanie, Cenas, Narimantas, Arnér, Elias S. J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268967/
https://ncbi.nlm.nih.gov/pubmed/18382651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001846
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