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SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases

SpvC is encoded by the Salmonella virulence plasmid. We have investigated the biochemical function of SpvC and the mechanism by which it is secreted by bacteria and translocated into infected macrophages. We constructed a strain carrying a deletion in spvC and showed that the strain is attenuated fo...

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Main Authors: Mazurkiewicz, Piotr, Thomas, Jerry, Thompson, Jessica A, Liu, Mei, Arbibe, Laurence, Sansonetti, Philippe, Holden, David W
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268955/
https://ncbi.nlm.nih.gov/pubmed/18284579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06134.x
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