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Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin

Curcumin has been extensively studied for its anti-inflammatory activities. However, its potential beneficial effects on various disease preventions and treatments are limited by its unstable structure. The β-diketone moiety renders curcumin to be rapidly metabolized by aldoketo reductase in liver....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liang, Guang, Li, Xiaokun, Chen, Li, Yang, Shulin, Wu, Xudong, Studer, Elaine, Gurley, Emily, Hylemon, Phillip B., Ye, Faqing, Li, Yueru, Zhou, Huiping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268908/
https://ncbi.nlm.nih.gov/pubmed/18234497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.12.068
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