Editing and escape from editing in anti-DNA B cells

Tolerance to dsDNA is achieved through editing of Ig receptors that react with dsDNA. Nevertheless, some B cells with anti-dsDNA receptors escape editing and migrate to the spleen. Certain anti-dsDNA B cells that are recovered as hybridomas from the spleens of anti-dsDNA H chain transgenic mice also...

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Dettagli Bibliografici
Autori principali: Khan, Salar N., Witsch, Esther J., Goodman, Noah G., Panigrahi, Anil K., Chen, Ching, Jiang, Yufei, Cline, Amy M., Erikson, Jan, Weigert, Martin, Prak, Eline T. Luning, Radic, Marko
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268806/
https://ncbi.nlm.nih.gov/pubmed/18310318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800025105
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