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Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation

Aging, defined as a decrease in reproduction rate with age, is a fundamental characteristic of all living organisms down to bacteria. Yet we know little about the causal molecular mechanisms of aging within the in vivo context of a wild-type organism. One of the prominent markers of aging is protein...

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Autori principali: Lindner, Ariel B., Madden, Richard, Demarez, Alice, Stewart, Eric J., Taddei, François
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268587/
https://ncbi.nlm.nih.gov/pubmed/18287048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708931105
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