Early Phosphatidylinositol 3-Kinase/Akt Pathway Activation Limits Poliovirus-Induced JNK-Mediated Cell Death

Poliovirus (PV)-induced apoptosis seems to play a major role in tissue injury in the central nervous system (CNS). We have previously shown that this process involves PV-induced Bax-dependent mitochondrial dysfunction mediated by early JNK activation in IMR5 neuroblastoma cells. We showed here that...

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Hlavní autoři: Autret, Arnaud, Martin-Latil, Sandra, Brisac, Cynthia, Mousson, Laurence, Colbère-Garapin, Florence, Blondel, Bruno
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268503/
https://ncbi.nlm.nih.gov/pubmed/18216097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02020-07
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