Emergence of Polyfunctional CD8(+) T Cells after Prolonged Suppression of Human Immunodeficiency Virus Replication by Antiretroviral Therapy

Progressive human immunodeficiency virus type 1 (HIV-1) infection is often associated with high plasma virus load (pVL) and impaired CD8(+) T-cell function; in contrast, CD8(+) T cells remain polyfunctional in long-term nonprogressors. However, it is still unclear whether CD8(+) T-cell dysfunction i...

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Autores principales: Rehr, Manuela, Cahenzli, Julia, Haas, Anna, Price, David A., Gostick, Emma, Huber, Milo, Karrer, Urs, Oxenius, Annette
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268491/
https://ncbi.nlm.nih.gov/pubmed/18199637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02383-07
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