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Rearrangements of Rotavirus Genomic Segment 11 Are Generated during Acute Infection of Immunocompetent Children and Do Not Occur at Random

Group A rotaviruses are the main cause of viral gastroenteritis in infants. The viral genome consists of 11 double-stranded RNA (dsRNA) segments. Dysfunction of the viral RNA polymerase can lead to gene rearrangements, which most often consist of partial sequence duplication of a dsRNA segment. Gene...

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Autores principales: Schnepf, Nathalie, Deback, Claire, Dehee, Axelle, Gault, Elyanne, Parez, Nathalie, Garbarg-Chenon, Antoine
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268475/
https://ncbi.nlm.nih.gov/pubmed/18216096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01770-07
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