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The Tight Junction Proteins Claudin-1, -6, and -9 Are Entry Cofactors for Hepatitis C Virus

Hepatitis C virus (HCV) is a major cause of liver disease in humans. The CD81 tetraspanin is necessary but not sufficient for HCV penetration into hepatocytes, and it was recently reported that the tight junction protein claudin-1 is a critical HCV entry cofactor. Here, we confirm the role of claudi...

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Main Authors: Meertens, Laurent, Bertaux, Claire, Cukierman, Lisa, Cormier, Emmanuel, Lavillette, Dimitri, Cosset, François-Loïc, Dragic, Tatjana
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268462/
https://ncbi.nlm.nih.gov/pubmed/18234789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01977-07
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