Redundancy and Plasticity of Neutralizing Antibody Responses Are Cornerstone Attributes of the Human Immune Response to the Smallpox Vaccine

The smallpox vaccine is widely considered the gold standard for human vaccines, yet the key antibody targets in humans remain unclear. We endeavored to identify a stereotypic, dominant, mature virion (MV) neutralizing antibody target in humans which could be used as a diagnostic serological marker o...

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Dettagli Bibliografici
Autori principali: Benhnia, Mohammed Rafii-El-Idrissi, McCausland, Megan M., Su, Hua-Poo, Singh, Kavita, Hoffmann, Julia, Davies, D. Huw, Felgner, Philip L., Head, Steven, Sette, Alessandro, Garboczi, David N., Crotty, Shane
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268460/
https://ncbi.nlm.nih.gov/pubmed/18234801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02244-07
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