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Homologous Recombination Is Necessary for Normal Lymphocyte Development
Primary immunodeficiencies are rare but serious diseases with diverse genetic causes. Accumulating evidence suggests that defects in DNA double-strand break (DSB) repair can underlie many of these syndromes. In this context, the nonhomologous end joining pathway of DSB repair is absolutely required...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268416/ https://ncbi.nlm.nih.gov/pubmed/18212067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02139-07 |
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