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Acetylation of Conserved Lysines in the Catalytic Core of Cyclin-Dependent Kinase 9 Inhibits Kinase Activity and Regulates Transcription

Promoter clearance and transcriptional processivity in eukaryotic cells are fundamentally regulated by the phosphorylation of the carboxy-terminal domain of RNA polymerase II (RNAPII). One of the kinases that essentially performs this function is P-TEFb (positive transcription elongation factor b),...

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Autori principali: Sabò, Arianna, Lusic, Marina, Cereseto, Anna, Giacca, Mauro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268415/
https://ncbi.nlm.nih.gov/pubmed/18250157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01557-07
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