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Survival Signaling by C-RAF: Mitochondrial Reactive Oxygen Species and Ca(2+) Are Critical Targets
Survival signaling by RAF occurs through largely unknown mechanisms. Here we provide evidence for the first time that RAF controls cell survival by maintaining permissive levels of mitochondrial reactive oxygen species (ROS) and Ca(2+). Interleukin-3 (IL-3) withdrawal from 32D cells resulted in ROS...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268412/ https://ncbi.nlm.nih.gov/pubmed/18212057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00683-07 |
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