IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice

IL-33, a new member of the IL-1 family, signals through its receptor ST2 and induces T helper 2 (Th2) cytokine synthesis and mediates inflammatory response. We have investigated the role of IL-33 in antigen-induced hypernociception. Recombinant IL-33 induced cutaneous and articular mechanical hypern...

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Detalhes bibliográficos
Main Authors: Verri, Waldiceu A., Guerrero, Ana T. G., Fukada, Sandra Y., Valerio, Daniel A., Cunha, Thiago M., Xu, Damo, Ferreira, Sérgio H., Liew, Foo Y., Cunha, Fernando Q.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268203/
https://ncbi.nlm.nih.gov/pubmed/18250323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712116105
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2268203/
https://ncbi.nlm.nih.gov/pubmed/18250323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712116105