ATF3 regulates MCMV infection in mice by modulating IFN-γ expression in natural killer cells

Activating transcription factor 3 (ATF3) is a negative regulator of proinflammatory cytokine expression in macrophages, and ATF3-deficient mice are more susceptible to endotoxic shock. Here, we demonstrate that ATF3 interacts with a cis-regulatory element of the IFN-γ gene in natural killer (NK) cel...

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Détails bibliographiques
Auteurs principaux: Rosenberger, Carrie M., Clark, April E., Treuting, Piper M., Johnson, Carrie D., Aderem, Alan
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268173/
https://ncbi.nlm.nih.gov/pubmed/18268321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712182105
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