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The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8

Screening for novel anticancer drugs in chemical libraries isolated from marine organisms, we identified the lipopeptide somocystinamide A (ScA) as a pluripotent inhibitor of angiogenesis and tumor cell proliferation. The antiproliferative activity was largely attributable to induction of programmed...

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Библиографические подробности
Главные авторы: Wrasidlo, Wolf, Mielgo, Ainhoa, Torres, Vicente A., Barbero, Simone, Stoletov, Konstantin, Suyama, Takashi L., Klemke, Richard L., Gerwick, William H., Carson, Dennis A., Stupack, Dwayne G.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268133/
https://ncbi.nlm.nih.gov/pubmed/18268346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712198105
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