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β-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction

G-protein-coupled receptors (GPCRs), also known as seven transmembrane receptors (7-TMRs), are the largest protein receptor superfamily in the body. These receptors and their ligands direct a diverse array of physiological responses, and hence have broad relevance to numerous diseases. As a result,...

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Hlavní autor: DeFea, K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268080/
https://ncbi.nlm.nih.gov/pubmed/18037927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707508
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