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G-protein-coupled receptor heteromers: function and ligand pharmacology
Almost all existing models for G-protein-coupled receptors (GPCRs) are based on the occurrence of monomers. Recent studies show that many GPCRs are dimers. Therefore for some receptors dimers and not monomers are the main species interacting with hormones/neurotransmitters/drugs. There are reasons f...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268068/ https://ncbi.nlm.nih.gov/pubmed/18037920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707571 |
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