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RSV Capsid Polymorphism Correlates with Polymerization Efficiency and Envelope Glycoprotein Content: Implications that Nucleation Controls Morphogenesis
We used cryo-electron tomography to visualize Rous Sarcoma Virus, the prototypic alpharetrovirus. Its polyprotein Gag assembles into spherical procapsids, concomitant with budding. In maturation, Gag is dissected into its matrix (MA), capsid (CA) and nucleocapsid (NC) moieties. CA reassembles into c...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268030/ https://ncbi.nlm.nih.gov/pubmed/18206161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.003 |
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