RSV Capsid Polymorphism Correlates with Polymerization Efficiency and Envelope Glycoprotein Content: Implications that Nucleation Controls Morphogenesis

We used cryo-electron tomography to visualize Rous Sarcoma Virus, the prototypic alpharetrovirus. Its polyprotein Gag assembles into spherical procapsids, concomitant with budding. In maturation, Gag is dissected into its matrix (MA), capsid (CA) and nucleocapsid (NC) moieties. CA reassembles into c...

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Detalhes bibliográficos
Main Authors: Butan, Carmen, Winkler, Dennis C., Heymann, J. Bernard, Craven, Rebecca C., Steven, Alasdair C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268030/
https://ncbi.nlm.nih.gov/pubmed/18206161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.003
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