Increased Efficacy of HIV-1 Neutralization by Antibodies at Low CCR5 Surface Concentration

It has been observed that some antibodies, including the CD4-induced (CD4i) antibody IgG X5 and the gp41-specific antibody IgG 2F5, exhibit higher neutralizing activity in PBMC-based assays than in cell line based assays (Binley et al., J. Virology, 2004, 78: 13232). It has been hypothesized that th...

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Bibliographic Details
Main Authors: Choudhry, Vidita, Zhang, Mei-Yun, Harris, Ilia, Sidorov, Igor A., Vu, Bang, Dimitrov, Antony S., Fouts, Timothy, Dimitrov, Dimiter S.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268024/
https://ncbi.nlm.nih.gov/pubmed/16904645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.07.163
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