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Increased Efficacy of HIV-1 Neutralization by Antibodies at Low CCR5 Surface Concentration
It has been observed that some antibodies, including the CD4-induced (CD4i) antibody IgG X5 and the gp41-specific antibody IgG 2F5, exhibit higher neutralizing activity in PBMC-based assays than in cell line based assays (Binley et al., J. Virology, 2004, 78: 13232). It has been hypothesized that th...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268024/ https://ncbi.nlm.nih.gov/pubmed/16904645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.07.163 |
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