A carregar...
Phosphorylation and ubiquitination of oncogenic mutants of β-catenin containing substitutions at Asp32
β-Catenin, a member of the Wnt signaling pathway, is downregulated by glycogen synthase kinase-3β (GSK-3β)-dependent phosphorylation of Ser/Thr residues in the N-terminus of the protein, followed by ubiquitination and proteosomal degradation. In human and rodent cancers, mutations that substitute on...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267883/ https://ncbi.nlm.nih.gov/pubmed/15064718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207634 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|