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Induction of ovarian cancer by defined multiple genetic changes in a mouse model system

We have developed a mouse model for ovarian carcinoma by using an avian retroviral gene delivery technique for the introduction of multiple genes into somatic ovarian cells of adult mice. Ovarian cells from transgenic mice engineered to express the gene encoding the avian receptor TVA were efficient...

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Detalhes bibliográficos
Main Authors: Orsulic, Sandra, Li, Yi, Soslow, Robert A., Vitale-Cross, Lynn A., Gutkind, J. Silvio, Varmus, Harold E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267863/
https://ncbi.nlm.nih.gov/pubmed/12086888
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