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A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance

Cell lines and tumors with defined genetic alterations provide ideal systems in which to test the molecular mechanisms of tumor sensitivity to pathway-targeted therapy. We have generated mouse ovarian epithelial tumor cell lines that contain various combinations of genetic alterations in the p53, c-...

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Detalhes bibliográficos
Main Authors: Xing, Deyin, Orsulic, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087513/
https://ncbi.nlm.nih.gov/pubmed/15860581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502256102
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