Enhanced response of human head and neck cancer xenograft tumors to Cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging

PURPOSE: Determine if the response of human head and neck cancer xenografts to cisplatin (CIS) could be enhanced with 2-deoxyglucose (2DG) and determine if 2-[F-18]-fluoro-2-deoxy-D-glucose (FDG) uptake correlated with responses to this drug combination. Determine if 2DG would enhance CIS-induced ra...

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Detalhes bibliográficos
Main Authors: Simons, Andrean L., Fath, Melissa A., Mattson, David M., Smith, Brian J., Walsh, Susan A., Graham, Michael M., Hichwa, Richard D., Buatti, John M., Dornfeld, Ken, Spitz, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267859/
https://ncbi.nlm.nih.gov/pubmed/17967311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2007.07.2343
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