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The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction

BACKGROUND: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are tolerated. The rise in available protein sequences continues to increase the power of techniques based on this principle....

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Hlavní autoři: Manning, Jonathan R, Jefferson, Emily R, Barton, Geoffrey J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267696/
https://ncbi.nlm.nih.gov/pubmed/18221517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-51
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