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A Marked Effect of Electroconvulsive Stimulation on Behavioral Aberration of Mice with Neuron-Specific Mitochondrial DNA Defects
We developed transgenic (Tg) mice modeling an autosomally inherited mitochondrial disease, chronic progressive external ophthalmoplegia, patients with which sometimes have comorbid mood disorders. The mutant animals exhibited bipolar disorder-like phenotypes, such as a distorted day–night rhythm and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267493/ https://ncbi.nlm.nih.gov/pubmed/18365022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001877 |
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