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Clostridial spores as live 'Trojan horse' vectors for cancer gene therapy: comparison with viral delivery systems

Solid tumours account for 90% of all cancers. Gene therapy represents a potential new modality for their treatment. Up to now, several approaches have been developed, but the most efficient ones are the viral vector based gene therapy systems. However, viral vectors suffer from several deficiencies:...

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Detalhes bibliográficos
Main Authors: Wei, Ming Q, Ren, Ruimei, Good, David, Anné, Jozef
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267465/
https://ncbi.nlm.nih.gov/pubmed/18279524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-6-8
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