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Human α(2)-macroglobulin is composed of multiple domains, as predicted by homology with complement component C3

Human α(2)M (α(2)-macroglobulin) and the complement components C3 and C4 are thiol ester-containing proteins that evolved from the same ancestral gene. The recent structure determination of human C3 has allowed a detailed prediction of the location of domains within human α(2)M to be made. We descri...

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Detalhes bibliográficos
Main Authors: Doan, Ninh, Gettins, Peter G. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267405/
https://ncbi.nlm.nih.gov/pubmed/17608619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070764
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