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Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4.

A comparison of the sequence of the subunit of human alpha 2-macroglobulin (alpha 2M; 1451 amino acid residues) with that of murine complement component pro-C3 (1639 amino acid residues) reveals eight extended regions of sequence similarity. These regions contain between 19% and 31% identically plac...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sottrup-Jensen, L, Stepanik, T M, Kristensen, T, Lønblad, P B, Jones, C M, Wierzbicki, D M, Magnusson, S, Domdey, H, Wetsel, R A, Lundwall, A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1985
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC396960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2578664/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.1.9
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