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Nucleolar localization of the Werner syndrome protein in human cells

Werner Syndrome (WS) is a human genetic disorder with many features of premature aging. The gene defective in WS (WRN) has been cloned and encodes a protein homologous to several helicases, including Escherichia coli RecQ, the human Bloom syndrome protein (BLM), and Saccharomyces cerevisiae Sgs1p. T...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Marciniak, Robert A., Lombard, David B., Johnson, F. Bradley, Guarente, Leonard
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9618508/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.12.6887
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