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PTEN is destabilized by phosphorylation on Thr(366)
Although PTEN (phosphatase and tensin homologue deleted on chromosome 10) is one of the most commonly mutated tumour suppressors in human cancers, loss of PTEN expression in the absence of mutation appears to occur in an even greater number of tumours. PTEN is phosphorylated in vitro on Thr(366) and...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Portland Press Ltd.
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267318/ https://ncbi.nlm.nih.gov/pubmed/17444818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061837 |
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