Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT29)

BACKGROUND AND PURPOSE: We investigated the ability of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, to modulate expression of ICAM-1 and VCAM-1 in the colon cancer cell line HT29. EXPERIMENTAL APPROACH: We analysed the effect of celecoxib on ICAM-1 and VCAM-1 protein and mRNA expressio...

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Autores principales: Gallicchio, M, Rosa, A C, Dianzani, C, Brucato, L, Benetti, E, Collino, M, Fantozzi, R
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2007
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267284/
https://ncbi.nlm.nih.gov/pubmed/18084318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707634
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