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Celecoxib modulates adhesion of HT29 colon cancer cells to vascular endothelial cells by inhibiting ICAM-1 and VCAM-1 expression

BACKGROUND AND PURPOSE: Cyclooxygenase-2 (COX-2) is highly expressed during inflammation and can promote the progression of colorectal cancer. Interactions between cancer cells and vascular endothelial cells are key events in this process. Recently, the selective COX-2 inhibitor, celecoxib, was show...

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Detalhes bibliográficos
Main Authors: Dianzani, C, Brucato, L, Gallicchio, M, Rosa, A C, Collino, M, Fantozzi, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275462/
https://ncbi.nlm.nih.gov/pubmed/18084316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707636
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