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Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes

BACKGROUND AND PURPOSE: Pulmonary veins are the most important focus for the generation of atrial fibrillation. Abnormal calcium homeostasis with ryanodine receptor dysfunction may underlie the arrhythmogenic activity in pulmonary veins. The preferential ryanodine receptor stabilizer (K201) possesse...

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Detalhes bibliográficos
Main Authors: Chen, Y-J, Chen, Y-C, Wongcharoen, W, Lin, C-I, Chen, S-A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267278/
https://ncbi.nlm.nih.gov/pubmed/17994112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707564
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