Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes

BACKGROUND AND PURPOSE: Pulmonary veins are the most important focus for the generation of atrial fibrillation. Abnormal calcium homeostasis with ryanodine receptor dysfunction may underlie the arrhythmogenic activity in pulmonary veins. The preferential ryanodine receptor stabilizer (K201) possesse...

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Bibliografiske detaljer
Main Authors: Chen, Y-J, Chen, Y-C, Wongcharoen, W, Lin, C-I, Chen, S-A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267278/
https://ncbi.nlm.nih.gov/pubmed/17994112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707564
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