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Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors

The non-receptor tyrosine kinase Src is recruited to activated fibroblast growth factor receptor (FGFR) complexes through the adaptor protein factor receptor substrate 2 (FRS2). Here, we show that Src kinase activity has a crucial role in the regulation of FGFR1 signalling dynamics. Following recept...

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Bibliografski detalji
Glavni autori: Sandilands, Emma, Akbarzadeh, Shiva, Vecchione, Anna, McEwan, David G, Frame, Margaret C, Heath, John K
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267225/
https://ncbi.nlm.nih.gov/pubmed/17975556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401097
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