Haplotype Reconstruction Error as a Classical Misclassification Problem: Introducing Sensitivity and Specificity as Error Measures

BACKGROUND: Statistically reconstructing haplotypes from single nucleotide polymorphism (SNP) genotypes, can lead to falsely classified haplotypes. This can be an issue when interpreting haplotype association results or when selecting subjects with certain haplotypes for subsequent functional studie...

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Bibliographic Details
Main Authors:	Lamina, Claudia, Bongardt, Friedhelm, Küchenhoff, Helmut, Heid, Iris M.
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2008
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2267219/ https://ncbi.nlm.nih.gov/pubmed/18365008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001853
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Haplotype Reconstruction Error as a Classical Misclassification Problem: Introducing Sensitivity and Specificity as Error Measures

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