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Protein Structure and Hydration Probed by SANS and Osmotic Stress

Interactions governing protein folding, stability, recognition, and activity are mediated by hydration. Here, we use small-angle neutron scattering coupled with osmotic stress to investigate the hydration of two proteins, lysozyme and guanylate kinase (GK), in the presence of solutes. By taking adva...

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Detalles Bibliográficos
Main Authors: Stanley, Christopher, Krueger, Susan, Parsegian, V. Adrian, Rau, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267150/
https://ncbi.nlm.nih.gov/pubmed/18178651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.122697
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