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Allosteric Activation of Na(+)-Ca(2+) Exchange by L-Type Ca(2+) Current Augments the Trigger Flux for SR Ca(2+) Release in Ventricular Myocytes

The possible contribution of Na(+)-Ca(2+) exchange to the triggering of Ca(2+) release from the sarcoplasmic reticulum in ventricular cells remains unresolved. To gain insight into this issue, we measured the “trigger flux” of Ca(2+) crossing the cell membrane in rabbit ventricular myocytes with Ca(...

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Detalhes bibliográficos
Main Authors: Sobie, Eric A., Cannell, Mark B., Bridge, John H. B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267144/
https://ncbi.nlm.nih.gov/pubmed/18223001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.127878
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