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Probing Intranuclear Environments at the Single-Molecule Level

Genome activity and nuclear metabolism clearly depend on accessibility, but it is not known whether and to what extent nuclear structures limit the mobility and access of individual molecules. We used fluorescently labeled streptavidin with a nuclear localization signal as an average-sized, inert pr...

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Hlavní autoři: Grünwald, David, Martin, Robert M., Buschmann, Volker, Bazett-Jones, David P., Leonhardt, Heinrich, Kubitscheck, Ulrich, Cardoso, M. Cristina
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267134/
https://ncbi.nlm.nih.gov/pubmed/18065482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.115014
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