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Notch Signaling Regulates Bile Duct Morphogenesis in Mice
BACKGROUND: Alagille syndrome is a developmental disorder caused predominantly by mutations in the Jagged1 (JAG1) gene, which encodes a ligand for Notch family receptors. A characteristic feature of Alagille syndrome is intrahepatic bile duct paucity. We described previously that mice doubly heteroz...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266994/ https://ncbi.nlm.nih.gov/pubmed/18365007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001851 |
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